Mic Articles

Spain and Chile: MAPKs are key signaling mechanisms for detoxification in Macroalgae

The role of the MAPK signaling pathway in U. compressa under chronic copper stress was investigated by studying the expression of selected genes using RT-qPCR performed on the MIC.

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Germany: DNA methylation determines TNF- α dependent regulation of ACE expression in human endothelial cells

Role of DNA methylation in the TNF-α dependent regulation of ACE expression was studied using RT-qPCR on MIC qPCR cycler.

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DNA extraction chip

South Korea: Modular Chip for Bacterial DNA Extraction

A modular chip was developed to simplify and reduce the cost of bacterial DNA extraction. The chip demonstrated high efficiency and reproducibility with similar performance to conventional methods. It can potentially be used for Point-of-Care testing.

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Fat Pad Stem Cells

Italy: Infrapatellar Fat Pad stem cells exert incomplete protective activity from OA inflammation

The study employed techniques, such as gene expression performed on the MIC, to determine the structural and functional characterization of osteoarthritic infrapatellar fat pad stem cells and their role in osteoarthritic inflammation.

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Sonic hedgehog hair growth

South Korea: Sonic Hedgehog protein promotes hair-related gene expression

The effect of overexpression of Shh protein on hair follicle growth was investigated using quantitative qPCR on the Mic Real-Time Cycler.

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RecQ helicase Blooms yndrome

USA: Functional conservation of RecQ helicase BLM between humans and Drosophila melanogaster

The extent of function conservation of RecQ helicases was investigated using quantitative qPCR on the Mic Real-Time Cycler.

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Australia Ascarisovawater

Australia: A propidium monoazide–qPCR (PMA-qPCR) method for detection of viable Ascaris ova in wastewater

A propidium monoazide–qPCR (PMA-qPCR) method was validated using the Mic qPCR cycler for detecting viable Ascaris ova in wastewater

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Poland Legionella

Poland: qPCR for the detection of Legionella spp. and E. Coli in hot tap water systems

In this study, L. spp., L. pneumophila, and E. coli bacteria were quantified from total DNA extracts of hot tap water samples using the MIC qPCR platform with TaqMan probes. The obtained results prove the presence of these bacteria in hot tap water installations in the majority of the examined buildings.

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Finland Olympiccolds

Finland: Molecular point-of-care testing for rapid diagnosis of common colds occurring in elite athletes

Molecular point-of-care testing (POCT) consists of a multiplex qPCR for rapid diagnosis of the aetiological agent causing the common cold. It allows for effective treatment and enhance timely isolation to decrease viral transmission.

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