Skip to main content
Hit enter to search or ESC to close
Close Search
Bio Molecular Systems
  • Products
    • Mic qPCR Cycler
    • Myra Liquid Handler
    • Mic IVD
  • About us
  • News
  • Login
  • Contact Us
  • Request a Demo

Spain and Chile: MAPKs are key signaling mechanisms for detoxification in Macroalgae

  • June 02, 2020

MAPK Pathway under Chronic Copper Excess in Green Macroalgae (Chlorophyta): Involvement in the Regulation of Detoxification Mechanisms

Fernanda Rodríguez-Rojas,Paula S. M. Celis-Plá, Lorena Méndez, Fabiola Moenne, Pamela T. Muñoz, M. Gabriela Lobos, Patricia Díaz, José Luis Sánchez-Lizaso, Murray T. Brown, Alejandra Moenne and Claudio A. Sáez|Laboratory of Aquatic Environmental Research, Centro de Estudios Avanzados, Universidad de Playa Ancha, Viña del Mar 2520000, Chile, HUB-AMBIENTAL UPLA, Universidad de Playa Ancha, Valparaíso 2340000, Chile, Doctorado Interdisciplinario en Ciencias Ambientales, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Valparaíso 2340000, Chile, Doctorado en Ciencias del Mar y Biología Aplicada, Departamento de Ciencias del Mar y Biología Aplicada, Universidad de Alicante, 03080 Alicante, Spain, Laboratory of Environmental and Analytical Chemistry, Instituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso 234000, Chile, Departamento de Ciencias del Mar y Biología Aplicada, Universidad de Alicante, 03080 Alicante, Spain, School of Biological and Marine Sciences, University of Plymouth, PL4 8AA Plymouth, UK, Laboratory of Marine Biotechnology, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170020, Chile|2019|PLoS ONE|1495): e0216218

Previous studies have shown that copper-stressed green macroalgae display high levels of lipid peroxidation, enhanced activity of APC, consumption of glytathione and increased ascorbate. This suggests that antioxidant response is transcriptionally regulated in green macroalgae under chronic copper excess. The relationship of the mitogen-activated protein kinases (MAPK) signally pathway to the regulation of antioxidant responses has not been previously investigated fully. In this study, Ulva compressa (U. compressa) were exposed to chronic copper excess to study three main MPK pathways (ending in ERK, JNK and p38) and their roles in within antioxidant responses and detoxification mechanisms associated with metal chelation. This was done through studying the expression of the selected genes (CAT, SOD, TRX, APX, DHAR, GS and 18S) over time using RT-qPCR performed on the MIC qPCR cycler. It was observed that when one MAPK pathway was blocked under copper, there was recovery and even enhancement of detoxification mechanisms, likely due to crosstalk within the MAPKs and/or other signaling processes. However, when more than one MAPK pathway as blocked under chronic copper stress, impairment of detoxification defenses occurred, demonstrating that MAPKs were key signaling mechanisms for detoxification in macroalgae.

Read More
  • Previous Project
  • Next Project

Ready to produce quality data faster?

DOWNLOAD THE SOFTWARE
REQUEST A DEMO
  • Mic
  • Myra
  • About us
  • News
  • Login/Register
Bio Molecular Systems

© 2023 Bio Molecular Systems – all rights reserved

  • BMS Privacy Policy
  • Mic qPCR Warranty
  • Myra Warranty
  • Contact
  • sales@biomolecularsystems.com

  • twitter
  • facebook
  • linkedin
  • youtube
Close Menu
  • Products
    • Mic qPCR Cycler
    • Myra Liquid Handler
    • Mic IVD
  • About us
  • News
  • Login
  • Contact Us
  • Request a Demo
Cookie NoticeThis website uses cookies to improve your user experience. Details on what cookies we use can be found in our privacy policy.
Accept
Read more
Manage Cookies
Cookie Box Settings
Cookie Box Settings
 

Privacy settings

Decide which cookies you want to allow.You can change these settings at any time. However, this can result in some functions no longer being available. For information on deleting the cookies, please consult your browser’s help function.Learn more about the cookies we use.

With the slider, you can enable or disable different types of cookies:

  • Block all
  • Essential
  • Functionality
  • Analytics
  • Advertising

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected

This website won't:

  • Remember your login details
  • Functionality: Remember social media settings
  • Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Tailor information and advertising to your interests based on e.g. the content you have visited before.
  • Advertising: Gather personally identifiable information such as name and location

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settings
  • Functionality: Remember selected region and country

This website won't:

  • Remember your login details
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Tailor information and advertising to your interests based on e.g. the content you have visited before.
  • Advertising: Gather personally identifiable information such as name and location

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settingsl Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions

This website won't:

  • Remember your login details
  • Advertising: Use information for tailored advertising with third parties
  • Advertising: Allow you to connect to social sites
  • Advertising: Identify device you are using
  • Advertising: Gather personally identifiable information such as name and location

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settingsl Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Use information for tailored advertising with third parties
  • Advertising: Allow you to connect to social sites
  • Advertising: Identify device you are using
  • Advertising: Gather personally identifiable information such as name and location

This website won't:

  • Remember your login details
Save & Close