Skip to main content
Hit enter to search or ESC to close
Close Search
Bio Molecular Systems
  • Products
    • Mic qPCR Cycler
    • Myra Liquid Handler
    • Mic IVD
  • About us
  • News
  • Login
  • Contact Us
  • Request a Demo

USA: Conserved epitopes between FIV and HIV

  • April 12, 2019

Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses

Bikash Sahay, Alek M. Aranyos, Meerambika Mishra, Andrew C. McAvoy, Marcus M. Martin, Riuyu Pu, Sayaka Shiomitsu, Keijiro Shiomitsu, Michael J. Dark, Missa P. Sanou, Shannon R. Roff, Mobeen H. Rathore and Janet K. Yamamoto | Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, USA, Biovalion: Clinical Research, 7951 Ponds Edge Ln, Zephyrhills, FL 33540-1973, USA, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, USA, Department of Comparative, Diagnostic & Population Medicine, College of Veterinary Medicine, University of Florida, USA, Merck & Co., 770 Sumneytown Pike, North Wales, PA 19486, USA, Charles River Laboratories Inc., 15 Worman’s Mill Court, Suite I, Frederick, MD 21701, USA, Education, and Service (UF CARES), University of Florida Center for HIV/AIDS Research, Jacksonville, FL 32209-6810, USA | 2019 | Viruses; vol. 11, no. 136 doi:10.3390/v11020136

Developing an effective HIV vaccine is crucial for eradicating the virus. In this study, evolutionarily conserved epitopes between feline and human immunodeficiency viruses (FIV and HIV) were determined by analysing overlapping peptides from retroviral genomes that induce both anti-FIV and anti-HIV T-cell immunity. The four identified conserved epitopes were developed into four multiple antigen peptides (MAPs) and tested as an FIV vaccine in cats. Vaccine immunogenicity was determined 3-6 weeks post-second vaccination by RT-qPCR, performed on the MIC Real-Time Cycler. The vaccine resulted in a protection rate of 66.3% in cats.

Read More
  • Previous Project
  • Next Project

Ready to produce quality data faster?

DOWNLOAD THE SOFTWARE
REQUEST A DEMO
  • Mic
  • Myra
  • About us
  • News
  • Login/Register
Bio Molecular Systems

© 2023 Bio Molecular Systems – all rights reserved

  • BMS Privacy Policy
  • Mic qPCR Warranty
  • Myra Warranty
  • Contact
  • sales@biomolecularsystems.com

  • twitter
  • facebook
  • linkedin
  • youtube
Close Menu
  • Products
    • Mic qPCR Cycler
    • Myra Liquid Handler
    • Mic IVD
  • About us
  • News
  • Login
  • Contact Us
  • Request a Demo
Cookie NoticeThis website uses cookies to improve your user experience. Details on what cookies we use can be found in our privacy policy.
Accept
Read more
Manage Cookies
Cookie Box Settings
Cookie Box Settings
 

Privacy settings

Decide which cookies you want to allow.You can change these settings at any time. However, this can result in some functions no longer being available. For information on deleting the cookies, please consult your browser’s help function.Learn more about the cookies we use.

With the slider, you can enable or disable different types of cookies:

  • Block all
  • Essential
  • Functionality
  • Analytics
  • Advertising

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected

This website won't:

  • Remember your login details
  • Functionality: Remember social media settings
  • Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Tailor information and advertising to your interests based on e.g. the content you have visited before.
  • Advertising: Gather personally identifiable information such as name and location

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settings
  • Functionality: Remember selected region and country

This website won't:

  • Remember your login details
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Tailor information and advertising to your interests based on e.g. the content you have visited before.
  • Advertising: Gather personally identifiable information such as name and location

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settingsl Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions

This website won't:

  • Remember your login details
  • Advertising: Use information for tailored advertising with third parties
  • Advertising: Allow you to connect to social sites
  • Advertising: Identify device you are using
  • Advertising: Gather personally identifiable information such as name and location

This website will:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settingsl Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track on the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Use information for tailored advertising with third parties
  • Advertising: Allow you to connect to social sites
  • Advertising: Identify device you are using
  • Advertising: Gather personally identifiable information such as name and location

This website won't:

  • Remember your login details
Save & Close