Argentina: HRM analysis for discrimination of native-American Y-haplogroup in DNA

Argentina: HRM analysis for discrimination of native-American Y-haplogroup in DNA

HRM analysis on the Mic qPCR cycler provides a quick and cost-effective test for detection of Q1a3a haplogroup in forensic samples.

Germany & USA: PIAS1 is not suitable as a therapeutic agent for urothelial cancer

Germany & USA: PIAS1 is not suitable as a therapeutic agent for urothelial cancer

Gene expression analysis using Mic qPCR Cycler on PIAS1 demonstrates that it plays a minor role in cell survival and DNA repair within urothelial cancer cells in vitro and should not be used as a therapeutic agent.

USA: Sexual transmission of Zika virus typically only occurs in acutely infected mice.

USA: Sexual transmission of Zika virus typically only occurs in acutely infected mice.

Quantitative RT-qPCR was used to determine the possibility of sexual transmission of zika virus from infected males in chronic stages of disease. The expression levels of ZIKV RNA in intravaginal inoculated and subcutaneous inoculation groups of female and male mice were evaluated.

Australia: LAMP assay for detection of clinically virulent aprV2 Dichelobacter nodosus in-field

Australia: LAMP assay for detection of clinically virulent aprV2 Dichelobacter nodosus in-field

In-field LAMP assay for detection of aprV2 Dichelobacter nodosus was compared to gold standard laboratory-based RT-qPCR assay performed on the Mic qPCR Cycler.

Germany: CycG and p53 are required for DNA damage repair in Drosophila melanogaster

Germany: CycG and p53 are required for DNA damage repair in Drosophila melanogaster

Gene expression analysis on three null alleles of cycG flies that were exposed to ionizing radiation treatment was performed on the Mic qPCR Cycler.

Italy: Infrapatellar Fat Pad stem cells exert incomplete protective activity from OA inflammation

Italy: Infrapatellar Fat Pad stem cells exert incomplete protective activity from OA inflammation

The study employed techniques such as gene expression, performed on the MIC, to determine the structural and functional characterisation of osteoarthritic infrapatellar fat pad stem cells and their role in osteoarthritic inflammation.

Spain and Chile: MAPKs are key signaling mechanisms for detoxification in Macroalgae

Spain and Chile: MAPKs are key signaling mechanisms for detoxification in Macroalgae

The role of the MAPK signaling pathway in U. compressa under chronic copper stress was investigated by studying the expression of selected genes using RT-qPCR performed on the MIC.

Germany: DNA methylation determines TNF- α dependent regulation of ACE expression in human endothelial cells

Germany: DNA methylation determines TNF- α dependent regulation of ACE expression in human endothelial cells

Role of DNA methylation in the TNF-α dependent regulation of ACE expression was studied using RT-qPCR on MIC qPCR cycler.

South Korea: Modular Chip for Bacterial DNA Extraction

South Korea: Modular Chip for Bacterial DNA Extraction

A modular chip was developed to simplify and reduce the cost of bacterial DNA extraction. The chip demonstrated high efficiency and reproducibility with similar performance to conventional methods. It can potentially be used for Point-of-Care testing.

Italy: Infrapatellar Fat Pad stem cells exert incomplete protective activity from OA inflammation

Italy: Infrapatellar Fat Pad stem cells exert incomplete protective activity from OA inflammation

The study employed techniques, such as gene expression performed on the MIC, to determine the structural and functional characterization of osteoarthritic infrapatellar fat pad stem cells and their role in osteoarthritic inflammation.