Israel: Synthetic Virology

Generation and comparative genomics of synthetic dengue viruses

Eli Goz, Yael Tsalenchuck, Rony Oren Benaroya, Zohar Zafrir, Shimshi Atar, Tahel Altman, Justin Julander and Tamir Tuller | Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel; SynVaccineLtd. Ramat Hachayal, Tel Aviv, Israel | 2018 | BMC Bioinformatics 2018, 19(Suppl 6):140

Synthetic viruses are genetically engineered to help explore novel approaches for development of vaccines and virus therapies. The authors developed a methodology for analysing their synthetically derived viruses using the Mic. They specifically looked at genetic variants of the dengue virus.